As the series progressed, I noticed that it ended up having a lot of very poorly inserted humor. While it was appreciative in the begining, when the storyline was lighter and less traumatic, Ed's outbursts and the Elrics' humorous sibling squabbles grew a bit tiresome and unfitting to the events that were occuring/occured. Most of the attempts to keep the series humorous during latter part of the series made me just go, "OW, PAIN."

If you're looking for 'ships in the series though, you might want to move away. Most of the canon subtext occurs in the latter 10-15 episodes of the series, and felt rushed. (Unless if you 'ship Elricest though.